Claude Code for Researchers
A comprehensive guide for researchers and analysts getting started with Claude Code for data analysis, scripting, and research workflows
Claude Code for Researchers
If you're a researcher, data analyst, or scientist looking to integrate AI into your workflow, Claude Code offers powerful capabilities that can transform how you work with data, write code, and manage research projects.
What Claude Code Can Do
Claude Code is a command-line AI assistant that lives in your terminal and can:
Direct File System Access
Unlike web-based AI assistants, Claude Code can directly read, write, and modify files on your computer:
# Claude can read your data files directlyclaude "analyze the CSV file in ./data/experiment_results.csv" # It can write scripts and save themclaude "create a Python script to clean this dataset and save it as clean_data.py" # It can even run your code and iterate on errorsclaude "run the analysis script and fix any errors"Execute Code in Real-Time
Claude Code can run Python, R, and shell commands, see the output, and iterate:
# Run analysis and get resultsclaude "run a statistical analysis on my survey data and show me the results" # Debug interactivelyclaude "this script is throwing an error - help me fix it"Understand Your Full Project Context
Claude Code can explore your entire codebase, not just single files:
# Get project-wide understandingclaude "explain how the data pipeline in this project works" # Find and modify across filesclaude "update all functions that use the old API format"Working with Python
Claude Code excels at Python-based research workflows. Here are practical examples:
Data Cleaning and Preprocessing
# Ask Claude to help clean messy data# "Clean this survey data: handle missing values, standardize date formats,# and remove duplicates" import pandas as pdimport numpy as np def clean_survey_data(filepath): """Clean and preprocess survey data.""" df = pd.read_csv(filepath) # Handle missing values df['age'] = df['age'].fillna(df['age'].median()) df['response'] = df['response'].fillna('No Response') # Standardize dates df['date'] = pd.to_datetime(df['date'], format='mixed') # Remove duplicates based on participant ID df = df.drop_duplicates(subset=['participant_id'], keep='first') return dfStatistical Analysis
# "Run a regression analysis on my experiment data with proper diagnostics" import pandas as pdimport statsmodels.api as smfrom scipy import stats def analyze_experiment(df, dependent_var, independent_vars): """Run regression with full diagnostics.""" X = df[independent_vars] X = sm.add_constant(X) y = df[dependent_var] model = sm.OLS(y, X).fit() # Print comprehensive results print(model.summary()) # Check assumptions residuals = model.resid print(f"\nNormality test (Shapiro-Wilk): {stats.shapiro(residuals)}") print(f"Homoscedasticity test (Breusch-Pagan): {sm.stats.diagnostic.het_breuschpagan(residuals, X)}") return modelVisualization
# "Create publication-ready figures for my results" import matplotlib.pyplot as pltimport seaborn as sns def create_publication_figure(df, x_var, y_var, group_var=None): """Create a publication-ready scatter plot with regression line.""" plt.figure(figsize=(10, 6)) if group_var: sns.scatterplot(data=df, x=x_var, y=y_var, hue=group_var, alpha=0.7) else: sns.regplot(data=df, x=x_var, y=y_var, scatter_kws={'alpha':0.5}) plt.xlabel(x_var.replace('_', ' ').title(), fontsize=12) plt.ylabel(y_var.replace('_', ' ').title(), fontsize=12) plt.title(f'{y_var.replace("_", " ").title()} vs {x_var.replace("_", " ").title()}', fontsize=14, fontweight='bold') plt.tight_layout() plt.savefig('figure.png', dpi=300, bbox_inches='tight') plt.savefig('figure.pdf', bbox_inches='tight') # Vector format for publications return plt.gcf()Machine Learning Pipelines
# "Build a classification model with cross-validation and feature importance" from sklearn.model_selection import cross_val_score, train_test_splitfrom sklearn.ensemble import RandomForestClassifierfrom sklearn.preprocessing import StandardScalerfrom sklearn.pipeline import Pipelineimport pandas as pd def build_classifier(df, target_col, feature_cols): """Build and evaluate a classification pipeline.""" X = df[feature_cols] y = df[target_col] # Create pipeline pipeline = Pipeline([ ('scaler', StandardScaler()), ('classifier', RandomForestClassifier(n_estimators=100, random_state=42)) ]) # Cross-validation cv_scores = cross_val_score(pipeline, X, y, cv=5, scoring='accuracy') print(f"Cross-validation accuracy: {cv_scores.mean():.3f} (+/- {cv_scores.std()*2:.3f})") # Fit and get feature importance pipeline.fit(X, y) importance = pd.DataFrame({ 'feature': feature_cols, 'importance': pipeline.named_steps['classifier'].feature_importances_ }).sort_values('importance', ascending=False) print("\nFeature Importance:") print(importance.to_string(index=False)) return pipeline, importanceWorking with R
Claude Code also supports R for statistical analysis. Here are examples:
Data Manipulation with tidyverse
# "Clean and reshape my longitudinal study data" library(tidyverse) clean_longitudinal_data <- function(filepath) { data <- read_csv(filepath) cleaned <- data %>% # Handle missing values mutate(across(where(is.numeric), ~replace_na(., median(., na.rm = TRUE)))) %>% # Standardize variable names rename_with(tolower) %>% rename_with(~str_replace_all(., " ", "_")) %>% # Convert to long format for repeated measures pivot_longer( cols = starts_with("time_"), names_to = "timepoint", values_to = "measurement", names_prefix = "time_" ) %>% # Create factors mutate( timepoint = factor(timepoint, levels = c("1", "2", "3")), group = factor(group) ) return(cleaned)}Statistical Modeling
# "Run a mixed-effects model for my repeated measures design" library(lme4)library(lmerTest)library(emmeans) analyze_repeated_measures <- function(data) { # Fit mixed-effects model model <- lmer( measurement ~ group * timepoint + (1 | participant_id), data = data ) # Print summary with p-values print(summary(model)) # Post-hoc comparisons emm <- emmeans(model, ~ group | timepoint) print(pairs(emm, adjust = "tukey")) # Effect sizes print(effectsize::eta_squared(model)) return(model)}Publication-Ready Plots with ggplot2
# "Create a figure showing group differences over time with error bars" library(ggplot2)library(ggpubr) create_longitudinal_plot <- function(data) { # Calculate summary statistics summary_data <- data %>% group_by(group, timepoint) %>% summarise( mean = mean(measurement, na.rm = TRUE), se = sd(measurement, na.rm = TRUE) / sqrt(n()), .groups = "drop" ) # Create plot p <- ggplot(summary_data, aes(x = timepoint, y = mean, color = group, group = group)) + geom_line(linewidth = 1) + geom_point(size = 3) + geom_errorbar(aes(ymin = mean - se, ymax = mean + se), width = 0.1) + labs( x = "Time Point", y = "Measurement (Mean +/- SE)", color = "Group", title = "Change in Measurement Over Time by Group" ) + theme_pubr() + theme( legend.position = "bottom", plot.title = element_text(hjust = 0.5, face = "bold") ) + scale_color_brewer(palette = "Set1") # Save in multiple formats ggsave("figure.png", p, width = 8, height = 6, dpi = 300) ggsave("figure.pdf", p, width = 8, height = 6) return(p)}Real-World Research Workflows
Example 1: Analyzing Survey Data
# Start a conversation with Claude Codeclaude # Then interact naturally:> "I have survey responses in data/survey.csv. Can you: 1. Load and explore the data 2. Check for missing values and outliers 3. Run reliability analysis on the Likert scale items 4. Create summary statistics by demographic groups 5. Export a clean dataset for further analysis"Example 2: Processing Multiple Data Files
claude "I have 50 CSV files in the experiments/ folder, each from a differentparticipant. Combine them into a single dataframe, add a participant ID columnbased on filename, and calculate summary statistics per participant."Example 3: Reproducing an Analysis
claude "Read the methods section in paper_notes.md and help me implementthe same statistical analysis on my replication data in data/replication.csv"Example 4: Debugging Complex Code
claude "My analysis script analysis.py is throwing a memory error whenprocessing large files. Help me optimize it to handle datasets over 10GB."Benefits for Researchers
Speed and Efficiency
| Task | Traditional Approach | With Claude Code | |------|---------------------|------------------| | Data cleaning script | 2-4 hours | 15-30 minutes | | Debugging complex code | Hours of Stack Overflow | Minutes of conversation | | Learning new library | Days of documentation | Guided examples in minutes | | Creating visualizations | Trial and error | Describe what you want |
Reproducibility
Claude Code helps maintain reproducible research:
- Documented workflows: Every command and modification is tracked
- Version control integration: Works seamlessly with Git
- Environment management: Helps set up virtual environments and dependencies
- Code comments: Generates well-documented, readable code
Learning Accelerator
For researchers learning to code:
- Explains concepts: Ask "why" about any code it writes
- Shows alternatives: Request different approaches to the same problem
- Teaches best practices: Suggests improvements to your existing code
- Adapts to your level: Provide more or less detail based on your expertise
Limitations to Be Aware Of
Data Privacy Considerations
IMPORTANT: Claude Code sends your prompts and relevant file contents toAnthropic's servers for processing. - Do NOT use with sensitive/identifiable participant data- Do NOT include API keys, passwords, or credentials in files- Consider using anonymized or synthetic data for development- Check your institution's policies on AI tool usageTechnical Limitations
| Limitation | Details | Workaround | |------------|---------|------------| | Context window | ~200K tokens per conversation | Break large analyses into steps | | No internet access | Can't fetch live data or APIs | Download data first, then analyze | | Computation limits | Complex ML training may timeout | Use for prototyping, run production elsewhere | | Package knowledge | May not know very new packages | Provide documentation or examples |
Research-Specific Considerations
- Verify statistical results: Always double-check statistical outputs against known software
- Code review: Review generated code before using in publications
- Citation: Consider how to acknowledge AI assistance in your methods
- Reproducibility: Save conversation logs for your records
Best Practices for Research Use
1. Start with Clear Prompts
# Good: Specific and detailedclaude "Load the CSV file data/experiment.csv, run a two-way ANOVA withfactors 'treatment' and 'time', check assumptions, and create an interaction plot" # Less effective: Vagueclaude "analyze my data"2. Iterate and Refine
# First passclaude "create a basic scatter plot of x vs y" # Refineclaude "add a regression line, confidence interval, and make it publication-ready" # Further refineclaude "change the color scheme to colorblind-friendly and add axis labels"3. Use Project Context Files
Create a CLAUDE.md file in your project root:
# Project: Effects of Sleep on Cognitive Performance ## Data Structure- data/raw/ - Original experiment data (do not modify)- data/processed/ - Cleaned datasets- analysis/ - R and Python scripts- figures/ - Output visualizations ## Analysis Standards- Use alpha = 0.05 for significance- Report effect sizes (Cohen's d or eta-squared)- All figures should be 300 DPI for publication ## Key Variables- dv: reaction_time (ms)- iv: sleep_condition (control, deprived, extended)- covariates: age, gender, caffeine_intake4. Maintain Audit Trails
# Save your Claude Code sessionsclaude --save-conversation analysis_session_2024.md # Or use git to track all changesgit add -A && git commit -m "Analysis updates via Claude Code"Getting Started Checklist
- [ ] Install Claude Code:
npm install -g @anthropic-ai/claude-code - [ ] Authenticate:
claude auth - [ ] Create project structure with clear folder organization
- [ ] Add a
CLAUDE.mdfile describing your project - [ ] Start with a small, non-sensitive dataset to learn the workflow
- [ ] Set up version control with Git
- [ ] Review your institution's AI usage policies
Next Steps
Ready to dive deeper? Start with these targeted resources:
For R1 Faculty & PIs
Research Case Studies
From raw data to publication in 30 minutes
Limitations & When Not to Use
Honest assessment for skeptical PIs
Collaboration Workflows
Working with grad students and co-authors
Grant & Manuscript Pipeline
BCO-DMO docs, supplements, reviewer responses
Hands-On Learning
- First 30 Minutes Exercise - Try it now with your own data
- Research Workflows Cheat Sheet - Printable quick reference (look for "Research Workflows")
- R/Tidyverse Cheat Sheet - Printable R reference
Deep Dives
- Python Data Analysis Track - Comprehensive Python tutorials
- R/Tidyverse Track - R-focused data analysis
- CLAUDE.md Generator - Create research project configs
- Git & GitHub Guide - Version control for reproducibility