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Claude Code for Researchers

A comprehensive guide for researchers and analysts getting started with Claude Code for data analysis, scripting, and research workflows

20 min
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Claude Code for Researchers

If you're a researcher, data analyst, or scientist looking to integrate AI into your workflow, Claude Code offers powerful capabilities that can transform how you work with data, write code, and manage research projects.

What Claude Code Can Do

Claude Code is a command-line AI assistant that lives in your terminal and can:

Direct File System Access

Unlike web-based AI assistants, Claude Code can directly read, write, and modify files on your computer:

Bash
# Claude can read your data files directly
claude "analyze the CSV file in ./data/experiment_results.csv"
# It can write scripts and save them
claude "create a Python script to clean this dataset and save it as clean_data.py"
# It can even run your code and iterate on errors
claude "run the analysis script and fix any errors"

Execute Code in Real-Time

Claude Code can run Python, R, and shell commands, see the output, and iterate:

Bash
# Run analysis and get results
claude "run a statistical analysis on my survey data and show me the results"
# Debug interactively
claude "this script is throwing an error - help me fix it"

Understand Your Full Project Context

Claude Code can explore your entire codebase, not just single files:

Bash
# Get project-wide understanding
claude "explain how the data pipeline in this project works"
# Find and modify across files
claude "update all functions that use the old API format"

Working with Python

Claude Code excels at Python-based research workflows. Here are practical examples:

Data Cleaning and Preprocessing

Python
# Ask Claude to help clean messy data
# "Clean this survey data: handle missing values, standardize date formats,
# and remove duplicates"
import pandas as pd
import numpy as np
def clean_survey_data(filepath):
"""Clean and preprocess survey data."""
df = pd.read_csv(filepath)
# Handle missing values
df['age'] = df['age'].fillna(df['age'].median())
df['response'] = df['response'].fillna('No Response')
# Standardize dates
df['date'] = pd.to_datetime(df['date'], format='mixed')
# Remove duplicates based on participant ID
df = df.drop_duplicates(subset=['participant_id'], keep='first')
return df

Statistical Analysis

Python
# "Run a regression analysis on my experiment data with proper diagnostics"
import pandas as pd
import statsmodels.api as sm
from scipy import stats
def analyze_experiment(df, dependent_var, independent_vars):
"""Run regression with full diagnostics."""
X = df[independent_vars]
X = sm.add_constant(X)
y = df[dependent_var]
model = sm.OLS(y, X).fit()
# Print comprehensive results
print(model.summary())
# Check assumptions
residuals = model.resid
print(f"\nNormality test (Shapiro-Wilk): {stats.shapiro(residuals)}")
print(f"Homoscedasticity test (Breusch-Pagan): {sm.stats.diagnostic.het_breuschpagan(residuals, X)}")
return model

Visualization

Python
# "Create publication-ready figures for my results"
import matplotlib.pyplot as plt
import seaborn as sns
def create_publication_figure(df, x_var, y_var, group_var=None):
"""Create a publication-ready scatter plot with regression line."""
plt.figure(figsize=(10, 6))
if group_var:
sns.scatterplot(data=df, x=x_var, y=y_var, hue=group_var, alpha=0.7)
else:
sns.regplot(data=df, x=x_var, y=y_var, scatter_kws={'alpha':0.5})
plt.xlabel(x_var.replace('_', ' ').title(), fontsize=12)
plt.ylabel(y_var.replace('_', ' ').title(), fontsize=12)
plt.title(f'{y_var.replace("_", " ").title()} vs {x_var.replace("_", " ").title()}',
fontsize=14, fontweight='bold')
plt.tight_layout()
plt.savefig('figure.png', dpi=300, bbox_inches='tight')
plt.savefig('figure.pdf', bbox_inches='tight') # Vector format for publications
return plt.gcf()

Machine Learning Pipelines

Python
# "Build a classification model with cross-validation and feature importance"
from sklearn.model_selection import cross_val_score, train_test_split
from sklearn.ensemble import RandomForestClassifier
from sklearn.preprocessing import StandardScaler
from sklearn.pipeline import Pipeline
import pandas as pd
def build_classifier(df, target_col, feature_cols):
"""Build and evaluate a classification pipeline."""
X = df[feature_cols]
y = df[target_col]
# Create pipeline
pipeline = Pipeline([
('scaler', StandardScaler()),
('classifier', RandomForestClassifier(n_estimators=100, random_state=42))
])
# Cross-validation
cv_scores = cross_val_score(pipeline, X, y, cv=5, scoring='accuracy')
print(f"Cross-validation accuracy: {cv_scores.mean():.3f} (+/- {cv_scores.std()*2:.3f})")
# Fit and get feature importance
pipeline.fit(X, y)
importance = pd.DataFrame({
'feature': feature_cols,
'importance': pipeline.named_steps['classifier'].feature_importances_
}).sort_values('importance', ascending=False)
print("\nFeature Importance:")
print(importance.to_string(index=False))
return pipeline, importance

Working with R

Claude Code also supports R for statistical analysis. Here are examples:

Data Manipulation with tidyverse

R
# "Clean and reshape my longitudinal study data"
library(tidyverse)
clean_longitudinal_data <- function(filepath) {
data <- read_csv(filepath)
cleaned <- data %>%
# Handle missing values
mutate(across(where(is.numeric), ~replace_na(., median(., na.rm = TRUE)))) %>%
# Standardize variable names
rename_with(tolower) %>%
rename_with(~str_replace_all(., " ", "_")) %>%
# Convert to long format for repeated measures
pivot_longer(
cols = starts_with("time_"),
names_to = "timepoint",
values_to = "measurement",
names_prefix = "time_"
) %>%
# Create factors
mutate(
timepoint = factor(timepoint, levels = c("1", "2", "3")),
group = factor(group)
)
return(cleaned)
}

Statistical Modeling

R
# "Run a mixed-effects model for my repeated measures design"
library(lme4)
library(lmerTest)
library(emmeans)
analyze_repeated_measures <- function(data) {
# Fit mixed-effects model
model <- lmer(
measurement ~ group * timepoint + (1 | participant_id),
data = data
)
# Print summary with p-values
print(summary(model))
# Post-hoc comparisons
emm <- emmeans(model, ~ group | timepoint)
print(pairs(emm, adjust = "tukey"))
# Effect sizes
print(effectsize::eta_squared(model))
return(model)
}

Publication-Ready Plots with ggplot2

R
# "Create a figure showing group differences over time with error bars"
library(ggplot2)
library(ggpubr)
create_longitudinal_plot <- function(data) {
# Calculate summary statistics
summary_data <- data %>%
group_by(group, timepoint) %>%
summarise(
mean = mean(measurement, na.rm = TRUE),
se = sd(measurement, na.rm = TRUE) / sqrt(n()),
.groups = "drop"
)
# Create plot
p <- ggplot(summary_data, aes(x = timepoint, y = mean, color = group, group = group)) +
geom_line(linewidth = 1) +
geom_point(size = 3) +
geom_errorbar(aes(ymin = mean - se, ymax = mean + se), width = 0.1) +
labs(
x = "Time Point",
y = "Measurement (Mean +/- SE)",
color = "Group",
title = "Change in Measurement Over Time by Group"
) +
theme_pubr() +
theme(
legend.position = "bottom",
plot.title = element_text(hjust = 0.5, face = "bold")
) +
scale_color_brewer(palette = "Set1")
# Save in multiple formats
ggsave("figure.png", p, width = 8, height = 6, dpi = 300)
ggsave("figure.pdf", p, width = 8, height = 6)
return(p)
}

Real-World Research Workflows

Example 1: Analyzing Survey Data

Bash
# Start a conversation with Claude Code
claude
# Then interact naturally:
> "I have survey responses in data/survey.csv. Can you:
1. Load and explore the data
2. Check for missing values and outliers
3. Run reliability analysis on the Likert scale items
4. Create summary statistics by demographic groups
5. Export a clean dataset for further analysis"

Example 2: Processing Multiple Data Files

Bash
claude "I have 50 CSV files in the experiments/ folder, each from a different
participant. Combine them into a single dataframe, add a participant ID column
based on filename, and calculate summary statistics per participant."

Example 3: Reproducing an Analysis

Bash
claude "Read the methods section in paper_notes.md and help me implement
the same statistical analysis on my replication data in data/replication.csv"

Example 4: Debugging Complex Code

Bash
claude "My analysis script analysis.py is throwing a memory error when
processing large files. Help me optimize it to handle datasets over 10GB."

Benefits for Researchers

Speed and Efficiency

| Task | Traditional Approach | With Claude Code | |------|---------------------|------------------| | Data cleaning script | 2-4 hours | 15-30 minutes | | Debugging complex code | Hours of Stack Overflow | Minutes of conversation | | Learning new library | Days of documentation | Guided examples in minutes | | Creating visualizations | Trial and error | Describe what you want |

Reproducibility

Claude Code helps maintain reproducible research:

  • Documented workflows: Every command and modification is tracked
  • Version control integration: Works seamlessly with Git
  • Environment management: Helps set up virtual environments and dependencies
  • Code comments: Generates well-documented, readable code

Learning Accelerator

For researchers learning to code:

  • Explains concepts: Ask "why" about any code it writes
  • Shows alternatives: Request different approaches to the same problem
  • Teaches best practices: Suggests improvements to your existing code
  • Adapts to your level: Provide more or less detail based on your expertise

Limitations to Be Aware Of

Data Privacy Considerations

Text
IMPORTANT: Claude Code sends your prompts and relevant file contents to
Anthropic's servers for processing.
- Do NOT use with sensitive/identifiable participant data
- Do NOT include API keys, passwords, or credentials in files
- Consider using anonymized or synthetic data for development
- Check your institution's policies on AI tool usage

Technical Limitations

| Limitation | Details | Workaround | |------------|---------|------------| | Context window | ~200K tokens per conversation | Break large analyses into steps | | No internet access | Can't fetch live data or APIs | Download data first, then analyze | | Computation limits | Complex ML training may timeout | Use for prototyping, run production elsewhere | | Package knowledge | May not know very new packages | Provide documentation or examples |

Research-Specific Considerations

  1. Verify statistical results: Always double-check statistical outputs against known software
  2. Code review: Review generated code before using in publications
  3. Citation: Consider how to acknowledge AI assistance in your methods
  4. Reproducibility: Save conversation logs for your records

Best Practices for Research Use

1. Start with Clear Prompts

Bash
# Good: Specific and detailed
claude "Load the CSV file data/experiment.csv, run a two-way ANOVA with
factors 'treatment' and 'time', check assumptions, and create an interaction plot"
# Less effective: Vague
claude "analyze my data"

2. Iterate and Refine

Bash
# First pass
claude "create a basic scatter plot of x vs y"
# Refine
claude "add a regression line, confidence interval, and make it publication-ready"
# Further refine
claude "change the color scheme to colorblind-friendly and add axis labels"

3. Use Project Context Files

Create a CLAUDE.md file in your project root:

Markdown
# Project: Effects of Sleep on Cognitive Performance
## Data Structure
- data/raw/ - Original experiment data (do not modify)
- data/processed/ - Cleaned datasets
- analysis/ - R and Python scripts
- figures/ - Output visualizations
## Analysis Standards
- Use alpha = 0.05 for significance
- Report effect sizes (Cohen's d or eta-squared)
- All figures should be 300 DPI for publication
## Key Variables
- dv: reaction_time (ms)
- iv: sleep_condition (control, deprived, extended)
- covariates: age, gender, caffeine_intake

4. Maintain Audit Trails

Bash
# Save your Claude Code sessions
claude --save-conversation analysis_session_2024.md
# Or use git to track all changes
git add -A && git commit -m "Analysis updates via Claude Code"

Getting Started Checklist

  • [ ] Install Claude Code: npm install -g @anthropic-ai/claude-code
  • [ ] Authenticate: claude auth
  • [ ] Create project structure with clear folder organization
  • [ ] Add a CLAUDE.md file describing your project
  • [ ] Start with a small, non-sensitive dataset to learn the workflow
  • [ ] Set up version control with Git
  • [ ] Review your institution's AI usage policies

Next Steps

Ready to dive deeper? Start with these targeted resources:

For R1 Faculty & PIs

Hands-On Learning

Deep Dives